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National Human Genome Research Institute (NHGRI)
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These resources have been reviewed and selected by STEM Learning’s team of education specialists for factual accuracy and relevance to teaching STEM subjects in UK schools.
How to sequence a genome
How to sequence a genome is a series of short step by step videos which break down the process on sequencing into mapping, building libraries, sub-cloning, E. coli, preparing DNA, sequencing, reading results.
Our molecular selves includes a dynamic 3-D video which takes you inside for a close-up look at how humans are made. Watch as the mysteries of the human genome are literally unraveled.
The last resource explores the ethics of DNA sequencing. A series of scenarios are presented and questions for discussion.
- The structure and function of DNA
- Overview of transcription and translation
- An outline of DNA sequencing
- Background information on the Human Genome Project
- Ethical issues
This resource is part of the Post 16 genetics and genomics collection.
Courtesy: National Human Genome Research Institute
Our molecular selves
How to sequence a genome: introduction
Mapping
Building libraries
Subclones
E. Coli storage
Preparing DNA for sequencing
Sequencing reactions
Products of sequencing reactions
Separating the sequencing products
Reading the sequencing products
Assembling the results
Working draft sequence
Conclusion
Ethics of DNA sequencing
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